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. 2021 Aug 12;15:722592. doi: 10.3389/fnins.2021.722592

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Copyright © 2021 Song, Liu, Yang, Lv, Li and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Meta-analysis of four large-scale genome-wide association studies (GWASs) identified two novel risk loci for epilepsy. Manhattan plot of the meta-analysis of epilepsy (26,352 cases and 7,74,517 controls). The risk loci on 7q21.11 (lead SNP rs11978015, p = 9.26 × 10^{– 9}) and 8p23.1 (lead SNP rs28634186, p = 4.39 × 10^{– 8}) are newly identified in the present study.