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. 2021 Aug 12;15:722592. doi: 10.3389/fnins.2021.722592

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Copyright © 2021 Song, Liu, Yang, Lv, Li and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Locuszoom plots of the three genome-wide significant (GWS) loci. (A) The lead SNP rs11890028 (P = 7.76 × 10^{– 13}) of the 2q24.3 risk locus resides in intronic region of SCN1A. (B) The lead SNP rs11978015 (P = 9.26 × 10^{– 9}) of the 7q21.11 risk locus resides upstream of GRM3. (C) The nearest gene for the lead SNP rs28634186 (P = 4.39 × 10^{– 8}) on the 8p23.1 is TNKS. The read dotted line represents the genome-wide significance level (5.0 × 10^{– 8}).