Table 3.

Adverse Events Diagnosed Among Vaccinated Residents by Previous SARS-CoV-2 Status

	No Previous SARS-CoV-2 Diagnosis or Positive Test n = 13,163		Previous SARS-CoV-2 Diagnosis or Positive Test With Symptoms n = 5617				Previous SARS-CoV-2 Diagnosis or Positive Test Without Symptoms n = 2138
	n	Unadjusted Rate Per 100,000∗	n	Unadjusted Rate Per 100,000∗	Previous Symptomatic Vs No Previous	Previous Symptomatic Vs Asymptomatic	n	Unadjusted Rate Per 100,000∗	Previous Asymptomatic Vs No Previous
					Adjusted Risk Ratio	Adjusted Risk Ratio
15-day event rates
Acute myocardial infarction	1	7.6 (1.3–43.0)	0	—	—	—	0	—	—
Bell’s palsy	1	7.6 (1.3–43.0)	0	—	—	—	0	—	—
Convulsions/Seizures	3	22.8 (7.8–67.0)	0	—	—	—	0	—	—
Stroke, hemorrhagic	1	7.6 (1.3–43.0)	0	—	—	—	0	—	—
Stroke, ischemic	1	7.6 (1.3–43.0)	0	—	—	—	0	—	—
Venous thromboembolism	4	30.4 (11.8–78.1)	0	—	—	—	1	46.8 (8.3–264.5)	1.77 (0.20–15.78)
Pulmonary embolism	1	7.6 (1.3–43.0)	0	—	—	—	0	—	—
7-day event rates
Death	93	706.5 (577.1–864.7)	31	551.9 (389.1–782.3)	0.61 (0.49–0.76)	1.20 (0.81–1.77)	12	561.3 (321.4–978.5)	0.51 (0.35–0.73)

Adjusted risk ratios: Inverse probability weighting was used to adjust the probability of previous SARS-CoV-2 diagnosis by age, gender, race/ethnicity, diabetes, chronic obstructive pulmonary disease, renal disease, hypertension, congestive heart failure, coronary heart disease, dementia, cognitive function, mortality risk and physical function.

Note: Residents with a positive SARS-CoV-2 test within 20 days of vaccination (because they should not have been vaccinated), or who were on monoclonal antibodies within 90 days of vaccination were excluded. Previous SARS-CoV-2 diagnosis or positive test were 21 or more days before vaccination. Symptoms presented within the 5 days before or up to 14 days after the previous SARS-CoV-2 diagnosis or positive test.

∗Wilson’s 95% CIs.