Table 5.
Plasma levels of apolipoprotein C-II and C-III vs. ABPM profile in CAKUT and non-CAKUT CKD children and adolescents.
| CAKUT ( n = 49) | Non-CAKUT ( n = 39) | |||||
|---|---|---|---|---|---|---|
| ApoC-II | ApoC-III | ApoC-II | ApoC-III | |||
| ABPM profile | N | Median (25th−75th) | Median (25th−75th) | N | Median (25th−75th) | Median (25th−75th) |
| 24-h BP | ||||||
| Abnormal | 4 | 4.68 (3.86–6.08) | 7.15 (6.14-8.38) | 8 | 7.35 (5.04–13.86) | 13.15 (8.5–20.33) |
| Normal | 45 | 5.36 (4.00–6.73) | 8.58 (7.02-10.94) | 31 | 4.82 (4.03–7.11) | 9.03 (7.49–10.83) |
| Awake BP | ||||||
| Abnormal | 5 | 4.69 (4.13–6.47) | 7.37 (6.32–8.13) | 9 | 6.25 (3.93–13.82) | 10.82 (6.93–19.01) |
| Normal | 44 | 5.32 (3.93–6.73) | 8.67 (7.01–10.95) | 30 | 5.09 (4.14–7.37) | 9.06 (7.74–10.9) |
| Asleep BP | ||||||
| Abnormal | 4 | 4.24 (3.65–4.69) | 7.15 (6.14–12.84) | 8 | 11.1 (5.79–15.67)* | 15.11 (10.44–20.33)* |
| Normal | 45 | 5.63 (4.29–6.73) | 8.58 (7.02–10.8) | 31 | 4.82 (4.03–7.08)* | 8.87 (7.49–10.5)* |
| BP load | ||||||
| Abnormal | 16 | 4.68 (3.61–6.17)* | 7.39 (6.53–8.72) | 16 | 5.94 (3.55–13.56) | 10.42 (7.52–15.29) |
| Normal | 33 | 5.63 (4.47–7.55)* | 8.94 (7.14–10.99) | 23 | 5.36 (4.44–7.11) | 9.03 (7.82–10.83) |
| Night dipping | ||||||
| Abnormal | 22 | 4.57 (3.65–6.34)* | 7.69 (6.6–9.2) | 14 | 5.99 (3.76–9.01) | 9.99 (7.47–12.58) |
| Normal | 27 | 6.23 (5.11–7.42)* | 8.75 (7.25–11.03) | 25 | 5.36 (4.31–8.25) | 9.03 (7.86–12.99) |
| ABPM profile | ||||||
| Abnormal | 28 | 4.81 (3.83–6.29)* | 7.83 (6.67–9.41) | 22 | 6.3 (3.76–11.27) | 9.9 (7.47–12.58) |
| Normal | 21 | 6.44 (5.19–7.55)* | 8.98 (7.04–11.32) | 17 | 4.82 (4.31–7.22) | 8.87 (7.87–9.99) |
ABPM, ambulatory blood pressure monitoring; CAKUT, congenital anomalies of the kidney and urinary tract; CKD, chronic kidney disease; BP, blood pressure.
*
p < 0.05 abnormal vs. normal group by the Mann–Whitney U-test.