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. 2021 May 8;156(2):123–132. doi: 10.1007/s00418-021-01985-y

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© The Author(s) 2021

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Fig. 2 — Interleukin treated scleral tissue undergoes collagen degradation. a–i Immunohistochemistry of Scx-GFP (green) and collagen hybridizing peptide (CHP, red, indicating collagen degradation). Compared to controls (a–c), a clear increase in signal intensity was evident in tissue incubated with IL1-ß (d–f) for both Scx-GFP and CHP that was abolished when treated with IL1-ß and dexamethasone (g–h). j Quantitative analysis of the signal increase of CHP j revealed statistical significance for IL-ß compared to IL1-ß and dexamethasone and control. Scale bars: 50 µm