Fig. 4.
Investigation of the molecular mechanisms by which CMA regulates lipid accumulation in macrophage. a and c The effect of different protease inhibitors, MG132 (a proteasome inhibitor), leupeptin (trypsin-like and cysteine protease inhibitor), and CQ (a lysosomal protease inhibitor), on the degradation of PLIN2. b, d, and e Analysis of the impact of CMA deficiency on the degradation of PLIN2 by western blot. ***p < 0.001 compared with control (NC or CTR), n = 3