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. 2020 Apr 13;14(4):661–669. doi: 10.1007/s12265-020-09986-3

Fig. 4.

Fig. 4

Investigation of the molecular mechanisms by which CMA regulates lipid accumulation in macrophage. a and c The effect of different protease inhibitors, MG132 (a proteasome inhibitor), leupeptin (trypsin-like and cysteine protease inhibitor), and CQ (a lysosomal protease inhibitor), on the degradation of PLIN2. b, d, and e Analysis of the impact of CMA deficiency on the degradation of PLIN2 by western blot. ***p < 0.001 compared with control (NC or CTR), n = 3