Table 2.
Overall findings at time of onset, 3 and 6-month follow-up.
| Baseline characteristics all cases of myocarditis | Time of symptom onset | 3-month follow-up | 6-month follow-up | 12-month follow-up | P Value |
|---|---|---|---|---|---|
| CMR/Echocardiography | n = 30 | n = 30 | n = 26 | n = 19 | |
| Mean LVEF (±SD) | 58 (±7.44) | 59 (±6) | 59.4 (±4.8) | 58 (±5.3) | NS |
| Resting ECG | n = 30 | n = 30 | n = 26 | n = 19 | |
| Number of malignant arrhythmias | 0 | 1 | 0 | 0 | NS |
| Number of benign arrhythmias | 8 | 6 | 4 | 4 | NS |
| 48-h-Holter ECG | n = 0 | n = 30 | n = 26 | n = 19 | |
| Number of malignant arrhythmias | / | 1 | 0 | 0 | NS |
| Number of benign arrhythmias | / | 6 | 6 | 4 | NS |
| Median APC/QRS % (IQR) | / | 0.0172 (0.008–0-047) | 0.036 (±0.055%) | 0.034 (0.002–0.06 | NS |
| Median PVC/QRS % (IQR) | / | 0.008 (0–0.0029) | 0. 16% (±0.782%) | 0.0026 (0–0.02) | NS |
| Exercise stress test | n = 0 | n = 29 | n = 25 | n = 19 | |
| Mean performance, watts (±SD) | / | 190 (±67) | 195 (±75) | 206 (±75) | NS |
| Mean % of predicted maximum watt | / | 95% (±27) | 98 (±26) | 105 (±26) | NS |
| Number of malignant arrhythmias | / | 0 | 0 | 0 | NS |
| Laboratory results (median) | n = 30 | n = 30 | n = 26 | n = 19 | |
| Mb, ng/l (IQR) | 32 (0–111) | 27 (0–40) | 22.7 (±31.1) | 27 (0–43) | 0.011 |
| TnT-hs, ng/l (IQR) | 350 (88–1104) | 2.5 (0–7) | 4.4 (±7.5) | 0 (0–7) | <0.001 |
| CK, U/l (IQR) | 238 (128–587) | 97 (66–156) | 130.3 (±63) | 119 (75–193) | 0.001 |
| NT-proBNP, ng/l (IQR) | 251 (45–676) | 30 (11–44) | 63 (±84) | 38 (13–121) | 0.05 |
| CRP, mg/l (IQR) | 21 (3–66) | 0.7 (0.4–2.6) | 1.6 (±1.8) | 0.9 (0.5–1.6) | <0.001 |
| Lc, G/L (IQR) | 7 (6–9) | 6.8 (5.9–7.2) | 5.9 (±2.3) | 6 (5.6–7.6) | NS |
Abbreviations: CMR = cardiac magnetic resonance imaging; SD = standard deviation; ECG = electrocardiogram; APC = atrial premature contraction; TnT-hs = high sensitivity troponin T, CK = creatine kinase; CRP = C-reactive protein; Lc = leukocytes; LVEF = left ventricular ejection fraction; Mb = myoglobin; NT-proBNP = NT-pro brain natriuretic peptide; NS = not significant; IQR = interquartile range; PVC = premature ventricular contraction