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. 2021 Aug 27;11:17304. doi: 10.1038/s41598-021-96812-8

Table 2.

Comparison of goal-directed benchmarks.

Benchmark Best of dataset SMILES LSTM SMILES GA Graph GA Graph MCTS cRNN EDM (ours)
Celecoxib red 0.505 1.000 0.607 1.000 0.378 1.000 1.000
Troglitazone red 0.419 1.000 0.558 1.000 0.312 1.000 1.000
Thiothixene red 0.456 1.000 0.495 1.000 0.308 1.000 1.000
LogP(− 1.0) 1.000 1.000 1.000 1.000 0.980 1.000 1.000
LogP(8.0) 1.000 1.000 1.000 1.000 0.979 1.000 1.000
TPSA(150.0) 1.000 1.000 1.000 1.000 1.000 1.000 1.000
CNS MPO 1.000 1.000 1.000 1.000 1.000 1.000 1.000
QED 0.948 0.948 0.948 0.948 0.944 0.948 0.948