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. 2021 Aug 27;11:17319. doi: 10.1038/s41598-021-96937-w

Table 3.

Comparison of preoperative laboratory indicators between the two groups.

Variables Without POP (N = 1945) With POP (N = 53) P value
TP < 65 g/L, n (%) 1185 (82.2) 47 (88.7) 0.222
ALB < 35 g/L, n (%) 975 (67.6) 37 (69.8) 0.737
GLOB (references 20–40 g/L), n (%) 0.693
< 20 228 (15.8) 7 (13.2)
> 40 12 (0.8) 0 (0.0)
A/G (references 1.2–2.4), n (%) 0.676
< 1.2 314 (21.8) 13 (24.5)
> 2.4 16 (1.1) 0 (0.0)
ALT (references 9–50 U/L), n (%) 0.431
< 9 162 (11.2) 8 (15.1)
> 50 72 (5.0) 1 (1.9)
AST (references 15–40 U/L), n (%) 0.807
< 15 269 (18.7) 9 (17.0)
> 40 140 (9.7) 4 (7.5)
TBIL (> 26), n (%) 192 (13.3) 9 (17.0) 0.442
DBIL (> 6), n (%) 648 (44.9) 30 (56.6) 0.145
IBIL (> 14), n (%) 242 (16.8) 10 (18.9) 0.061
ALP (references 45–125 U/L), n (%) 0.720
< 45 169 (11.7) 7 (13.2)
> 125 92 (6.4) 2 (3.8)
GGT (references 10–60 U/L), n (%) 0.936
< 10 83 (5.8) 3 (5.7)
> 60 116 (8.0) 5 (9.4)
CHE (references 5–12 U/L), n (%) 0.254
< 2 627 (43.5) 29 (54.7)
> 12 5 (0.3) 0 (0.0)
TBA (references 1–10 μmol/L), n (%) 0.411
< 1 91 (6.3) 3 (5.7)
> 10 164 (11.4) 3 (5.7)
HCRP (> 8 mg/L), n (%) 1210 (83.9) 45 (84.9) 0.846
CK (> 310 U/L), n (%) 297 (20.6) 11 (20.8) 0.978
CKMB (> 20 U/L), n (%) 219 (15.2) 14 (26.4) 0.027
LDH (> 250 U/L), n (%) 461 (32.0) 16 (30.2) 0.785
TC (> 5.2 μmol/L), n (%) 95 (6.6) 2 (3.8) 0.414
TG (> 1.7 μmol/L), n (%) 99 (6.9) 4 (7.5) 0.847
Na (references 137–147 mmol/L), n (%) 0.471
< 137 663 (46.0) 26 (49.1)
> 147 9 (0.6) 1 (1.9)
K (references 3.5–5.3 mmol/L), n (%) 0.610
< 3.5 205 (14.2) 6 (11.3)
> 5.3 16 (1.1) 0 (0.0)
CL (references 99–110 mmol/L), n (%) 0.050
< 99 225 (15.6) 65 (4.5)
> 110 65 (4.5) 6 (11.3)
TCO2 (references 20–30 mmol/L), n (%) 0.889
< 20 69 (4.8) 3 (5.7)
> 30 721 (5.0) 2 (3.8)
GLU (> 6.1), n (%) 868 (60.2) 34 (64.2) 0.761
UREA (> 8), n (%) 327 (22.8) 15 (28.3) 0.320
CREA (references 57–97 mmol/L), n (%) 0.563
< 57 623 (43.2) 20 (37.7)
> 97 92 (6.4) 5 (9.4)
UA (references 208–428 mmol/L), n (%) 0.302
< 208 729 (40.6) 22 (41.5)
> 428 44 (3.1) 3 (5.7)
CA (references 2.11–2.52 mmol/L), n (%) 0.600
< 2.11 761 (52.8) 31 (58.5)
> 2.52 12 (0.8) 0 (0.0)
P (references 0.85–1.51 mmol/L), n (%) 0.579
< 0.85 185 (12.8) 9 (17.0)
> 1.51 50 (3.5) 1 (1.9)
Mg (references 0.75–1.02 mmol/L), n (%) 0.671
< 0.75 167 (11.6) 44 (3.1)
> 1.02 8 (15.1) 1 (1.9)
BNP (ng/L), n (%) < 0.001
< 75 558 (38.7) 9 (17.0)
> 75 416 (28.8) 30 (56.6)
Unknown 468 (32.5) 14 (26.4)
WBC (references 3.5–9.5 × 109/L), n (%) 0.307
< 3.5 10 (0.7) 0 (0.0)
> 9.5 513 (35.6) 24 (45.3)
NEU (references 2.8–6.3 × 109/L), n (%) 0.071
< 1.8 3 (0.3) 0 (0.0)
> 6.3 749 (51.9) 36 (67.9)
LYM (references 1.1–3.2 × 109/L), n (%) 0.818
< 1.1 752 (52.1) 29 (54.7)
> 3.2 8 (0.6) 0 (0)
MON (references 0.1–0.6 × 109/L), n (%) 0.520
< 0. 1 3 (0.2) 0 (0)
> 0.6 870 (60.3) 36 (67.9)
EOS (references 0.02–0.05 × 109/L), n (%) 0.052
< 0.02 373 (25.9) 9 (17.0)
> 0.52 4 (0.3) 1 (1.9)
BAS (> 0.06), n (%) 83 (5.8) 3 (5.7) 0.977
RBC (> 5.8), n (%) 94 (6.5) 4 (7.5) 0.766
NEU% (references 45–75%), n (%) 0.650
< 45 3 (0.2) 0 (0.0)
> 75 865 (60.0) 35 (66.0)
LYM% (> 5.2), n (%) 1378 (95.6) 50 (94.3) 0.673
MON% (references 3–10%), n (%) 0.638
< 3 24 (1.7) 0 (0.0)
> 10 343 (23.8) 13 (24.5)
BAS% (> 1%), n (%) 10 (0.7) 11 (0.7) 0.318
HGB (< 110/120 g/L), n (%) 1334 (92.5) 50 (94.3) 0.618
MCV (references 82–100 fL), n (%) 0.086
< 82 31 (2.1) 0 (0.0)
> 100 110 (7.6) 8 (15.1)
MCH (references 27–34 pg), n (%) 0.189
< 27 38 (2.6) 0 (0.0)
> 34 92 (6.4) 6 (11.3)
MCHC (references 316–354 g/L), n (%) 0.074
< 316 38 (2.6) 3 (5.7)
> 354 61 (4.2) 5 (9.4)
RDW (references 11.6–16.5%), n (%) 0.912
< 11.6 5 (0.3) 0 (0.0)
> 16.5 136 (9.4) 5 (9.4)
PLT (references 125–350 × 109/L), n (%) 0.996
< 125 135 (9.4) 5 (9.4)
> 250 86 (6.0) 3 (5.7)
MPV (references 7.4–11.0 fL), n (%) 0.246
< 7.4 227 (15.7) 12 (22.6)
> 11.0 49 (3.4) 3 (5.7)
PCT (references 0.16–0.43%), n (%) 0.010
< 0.16 937 (65.0) 34 (64.2)
> 0.43 7 (0.5) 2 (3.8)
PDW (references 12.0–18.1%), n (%) 0.934
< 7.4 130 (9.0) 4 (7.5)
> 11.0 26 (1.8) 1 (1.9)
PT (> 12.5 S), n (%) 333 (23.1) 10 (18.9) 0.246
PTA (< 80%), n (%) 175 (12.1) 7 (13.2) 0.873
INR (> 1.4%), n (%) 11 (0.8) 1 (1.9) 0.368
APTT (references 28–42 S), n (%) 0.934
< 28 500 (34.7) 24 (45.3)
> 42 20 (1.4) 0 (0.0)
APTT-R (references 0.7–1.3), n (%) 0.528
< 0.7 18 (1.2) 0 (0.0)
> 1.3 16 (1.1) 0 (0.0)
TT (references 14–21 S), n (%) 0.696
< 14 1026 (71.2) 35 (66.0)
> 21 151 (10.5) 6 (11.3)
FIB (reference 2.0–4.4 mg/L), n (%) 0.708
< 2.0 16 (1.1) 0 (0.0)
> 4.4 350 (24.3) 14 (26.4)
ATIII (reference 80–120%), n (%) 0.916
< 80 295 (20.5) 12 (22.6)
> 120 33 (2.3) 1 (1.9)
D-Dimer (> 2.26 mg/L), n (%) 571 (39.6) 34 (64.2) < 0.001

ASA American Society of Anesthesiologists, BMI body mass index, TP total protein, ALB albumin, GLOB globulin, A/G values albumin/globulin, ALT alanine transaminase, AST aspartate aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, ALP alkaline phosphatase, GGT γ-glutamyl transpeptidase, CHE cholinesterase, TBA total bile acid, HCRP hypersensitive c-reactive protein, LDH lactate dehydrogenase, CREA creatinine, UA uric acid, CA calcium, P phosphorus, Mg magnesium, BNP brain natriuretic peptide, WBC white blood cell, NEUT neutrophile, LYM lymphocyte, MON mononuclear cell, EOS eosinophilic granulocyte, BAS basophilic granulocyte, RBC red blood cell, reference range: female, 3.5–5.0 × 1012/L; males, 4.0–5.5 × 1012/L. HGB hemoglobin, reference range: females, 110–150 g/L; males, 120–160 g/L, HCT haematocrit, 40–50%, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, RDW red blood cell distribution width, PLT platelet, 100–300 × 109/L, MPV mean platelet volume, PCT procalcitonin, pdw platelet distribution width, PT prothrombin time, PTA prothrombin activity, INR international normalized ratio, APTT activated partial thromboplastin time, APTT-R activated partial thromboplastin time ratio, TT thrombin time, TT-R thrombin ratio, FIB fibrinogen, ATIII antithrombin III.