Table 2.
Echocardiographic data of mice from different groups.
| Parameter | Groups | |||
|---|---|---|---|---|
| Control (n = 15) | Model (n = 15) | Model + AMD3100 (n = 15) | AMD3100 (n = 15) | |
| Body weight (g) | 23.78 ± 0.27 | 23.92 ± 0.75 | 23.62 ± 0.55 | 23.82 ± 0.68 |
| IVSd (mm) | 0.82 ± 0.04 | 0.82 ± 0.06 | 0.77 ± 0.03 | 0.82 ± 0.04 |
| IVSs (mm) | 1.14 ± 0.07 | 1.19 ± 0.06 | 1.08 ± 0.05 | 1.19 ± 0.07 |
| LVIDd (mm) | 3.36 ± 0.09 | 3.49 ± 0.12 | 3.47 ± 0.08 | 3.42 ± 0.11 |
| LVIDs (mm) | 2.26 ± 0.13 | 2.35 ± 0.11 | 2.48 ± 0.09 | 2.24 ± 0.14 |
| LVPWd (mm) | 0.63 ± 0.02 | 0.69 ± 0.03 | 0.68 ± 0.02 | 0.71 ± 0.02 |
| LVPWs (mm) | 1.05 ± 0.06 | 1.00 ± 0.05 | 0.98 ± 0.05 | 1.04 ± 0.05 |
| LVEF (%) | 61.57 ± 2.88 | 61.77 ± 1.94 | 60.66 ± 2.28 | 65.27 ± 2.64 |
| LVFS (%) | 33.04 ± 2.30 | 32.65 ± 1.37 | 32.17 ± 1.76 | 35.36 ± 1.92 |
| MV A (mm/s) | 175.77 ± 13.56 | 228.89 ± 41.84 | 179.60 ± 23.95 | 246.27 ± 91.91 |
| MV E (mm/s) | 319.68 ± 10.97 | 303.55 ± 10.90 | 286.92 ± 17.48 | 290.43 ± 24.09 |
| MV E/A ratio | 1.94 ± 0.14 | 1.89 ± 0.24 | 1.79 ± 0.12 | 1.88 ± 0.16 |
LVIDd left ventricular internal diameter at end-diastole, LVIDs left ventricular internal diameter at end-systole, LVPWd left ventricular posterior wall thickness at end-diastole, LVPWs left ventricular posterior wall thickness at end-systole, IVSd, interventricular septal thickness at end-diastole, IVSs, interventricular septal thickness at end-systole, LVEF left ventricular ejection fraction, LVFS left ventricular fractional shortening, MV E mitral valve E wave, MV A mitral valve A wave.
All data are presented as means ± SEM, and n represents the number of animals in each group.