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. 2021 Mar 17;15(9):2627–2642. doi: 10.1038/s41396-021-00956-4

Fig. 7. OLFM4 regulates inflammatory responses to P. gingivalis.

Fig. 7

A Hierarchical clustering heatmap based on RNA-Seq log (RPKM) values of inflammatory genes differentially regulated in by challenge with P. gingivalis (Pg) in TIGKs transiently transfected with siRNA to OLFM4 or scrambled siRNA (siC). Color intensity denotes level of gene expression by z-score. B qRT-PCR of CXLCL10 transcripts and C ELISA of CXCLC10 protein in supernatants of TIGKs transiently transfected with siRNA to OLFM4 or scrambled siRNA (siC) and challenged with P. gingivalis (Pg) or left uninfected (NI). Data are means with SD and representative of 3 biological replicates. ****p < 0.001.