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Pre-specified decision rules for the CLARITY trial. Details about how these probabilities are evaluated/approximated are available in the statistical analysis plan
| Reason for stopping | Posterior probability | Decision rule |
|---|---|---|
| Effectiveness | Pr(OR < log(1.00)) > 0.975 | > 0.95 |
| Futility | Pr(OR < log(1.00)) > 0.975 | < 0.02 |
