Table 2.

Net efflux ratios (r_net) of [³H]citalopram, [³H]paroxetine and [³H]sertraline across MDCKII-P-gp, MDCKII-BCRP and MDCKII-MRP2 monolayers. Data shown are means ± SD; n = 3.

Efflux Transporter	Citalopram	Paroxetine	Sertraline
MDCKII-P-gp	2.75 ± 0.79	1.39 ± 0.30	1.17 ± 0.20
MDCKII-BCRP	1.18 ± 0.32	0.92 ± 0.02	1.11 ± 0.61
MDCKII-MRP2	0.61 ± 0.11	-	1.69 ± 0.36

Abbreviation: r_net—efflux ratios obtained for P-gp-, BCRP- and MRP2-transfected MDCKII cells, normalized to the ratio obtained for the parental cells.