Table 1.

Datasets used in the convergent functional genomic analysis.

Organism	Reference	GEO Number	Design	Creatine	Control	Platform
Human	[70]	GSE7877	Expression profiling of vastus lateralis muscle in a randomized, placebo- controlled, crossover, double-blind design in young, healthy, non-obese men supplemented with CrM vs. placebo (dextrose) for ten days	12	12	Buck Institute_Homo sapiens_25K_verC
Mouse	[71]	GSE5140	Analysis of brains of C57Bl/6J animals fed a Cr-supplemented diet for six months	6	7	Affymetrix Mouse Genome 430 2.0 Array
Mouse	[72]	GSE42356	3T3 fibroblasts overexpressing CRT were treated with 5mM CrM	3	3	Illumina MouseWG-6 v2.0 expression beadchip