Table 3.

Information of predicted miRNAs interacting with the list of genes from the CFG analysis.

MicroRNA	Relevant Information
miR-1-3p	Suppresses the proliferation of hepatocellular carcinoma [129] and slows the proliferation and invasion of gastric [130] and lung adenocarcinoma [131].
miR-218-5p	Significantly upregulated during myogenic differentiation after activating the IGF-1 and MAPK/ERK pathways [132].
miR-134-5p	Lower levels are found in prostate cancer compared to benign prostatic hyperplasia [133]. In addition, it might have neuroprotective effects by regulating the miR-134-5p/CREB pathway in both humans and mice [134].
miR-5694	Mediates downregulation of AF9 (a subunit of the super elongation complex and associates with the histone methyltransferases) and provides metastatic advantages in basal-like breast cancer cells [135].
miR-320a	Although associated with certain types of cancer, it has been shown to inhibit the proliferation and progression of melanoma [136] and gastric adenocarcinoma [137].
miR-200b-3p	Higher expression is found in prostate cancer compared to benign prostatic hyperplasia [133].
miR-126a-3p	It targets low-density lipoprotein-receptor-related protein 1 and blocks WNT signaling, which partially explain the anti-tumor effects of curcumin [138].
miR-378a-3p	Exhibits tumor-suppressive and anti-metastatic effects in esophageal squamous cell carcinoma [139] and glioblastoma multiforme [140]; however, miR-378a might also have a pro-angiogenic effect on myoblasts and control vascularization of skeletal muscle [141].