3TC	lamivudine
AβP	amyloid β-peptide
ABC	abacavir
AD	Alzheimer’s disease
AGO	Argonaute protein
AIDS	acquired immunodeficiency syndrome
APP	amyloid-β precursor proteinARV–antiretroviral
ATV	atazanavir
Au	gold
AUC	area under the curve
AV	aloe vera
AZT	zidovudine
AZT-M	zidovudine myristate
AZTTP	azidothymidine 5′-triphosphate
BBB	blood-brain barrier
BHT	butylated hydroxy toluene
Brij®-35	polyoxyethylene (23) lauryl ether
BSA	bovine serum albumin
CAB	cabotegravir
Capmul® MCM	mono/diglyceride of caprylic acid
Capmul® MCM EP	glycerol monocaprylocaprate
Capmul® PG 8	propylene glycol monocaprylate
CapryolTM 90	propylene glycol monocaprylate
Captex® P 500	triglycerides and esters prepared from fractionated vegetable oil sources and fatty acids from coconuts and palm kernel oils
CC50	concentration at which 50% cells are viable
cART	combined antiretroviral therapy
CaSki	epidermoid cervical cancer cell line
CCR5	C-C chemokine receptor type 5
CD4	cluster of differentiation 4
Chol	cholesterol
Cmax	maximum concentration
CNS	central nervous system
Compritol® 888 ATO	glycerol dibehenate
COVID-19	coronavirus disease 2019
Cremophor® EL	castor oil fatty acids, ethoxylated glycerol ester
Cremophor® RH 40	polyoxyl 40 hydrogenated castor oil
CTAB	cetyltrimethylammonium bromide
d4T	stavudine
DCP	dicetyl phosphate
ddC	zalcitabine
ddI	didanosine
ddI EC	enteric coated didanosine
Dex–Prot	dextran–protamine;
D.L.	drug loading
DLV	delavirdine
DMPC	1,2-dimyristoyl-sn-glycero-3-phosphocholine
DMPE	1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine
DMPG	1,2-dimyristoyl-sn-glycero-3-phospho-(1′-rac-glycerol)
DNA	deoxyribonucleic acid
DODAB	dioctadecyl dimethylammonium bromide
DOPC	1,2-dioleoyl-sn-glycero-3-phosphocholine
DOPE	1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
DOR	doravirine
DPPC	1,2-dipalmitoyl-sn-glycero-3-phosphocholine
DPPE-PEG2000	1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-(polyethylene glycol)-2000]
DPPG	1,2-dipalmitoyl-sn-glycero-3-phospho-(1′-rac-glycerol)
DPTAP	1,2-dipalmitoyl-3-trimethylammonium-propane (chloride salt)
DRV	darunavir
DSPC	1,2-distearoyl-sn-glycero-3-phosphocholine
DSPE	1,2-distearoyl-sn-glycero-3-phosphorylethanolamine
DSPG	1,2-distearoyl-sn-glycero-3-phospho-(1′-rac-glycerol)
DTG	dolutegravir
Dynasan® 114	trimyristin
Dynasan® 118	glyceryl tristearate
EDPPC	cationic 1,2-dipalmitoylethyl-phosphatidylcholine
E.E.	entrapment efficiency
EFV	efavirenz
EPC	egg phosphatidylcholine
ETR	etravirine
EVG	elvitegravir
FIs	fusion inhibitors
FPV	fosamprenavir
FTC	emtricitabine
FTR	fostemsavir tromethamine
GC	glyceryl caprylate
Gelucire® 44/14	lauroyl polyoxyl-32 glycerides
Gelucire® 50/13	stearoyl polyoxyl-32 glycerides
GI	gastrointestinal
GMO	glyceryl monooleate/monoolein
GMS	glyceryl monostearate
gp41	glycoprotein gp41
gp120	glycoprotein gp120
GRAS	generally recognized as safe
HAART	highly effective antiretroviral therapy
HBMECs	human brain microvascular endothelial cells
HEC-1-A	human endometrial cancer-1
HG	hydrogel
HIV	human immunodeficiency virus
HSA	human serum albumin
HSPC	hydrogenated soy phosphatidylcholine
IBA	ibalizumab-uiyk
IDV	indinavir
II	integrase inhibitors
Labrasol®	caprylocaproyl polyoxyl-8 glycerides
LauroglycolTM	90 propylene glycol monolaurate
LDL	low-density lipoproteins
LFA-1	lymphocyte function-associated antigen 1
Lipoid® S 75	fat-free soybean phospholipids with 70% PC
logP	partition coefficient
LP	liposome
LPV	lopinavir
mAb	83-14 monoclonal antibody
Maisine® 35-1	glyceryl monolinoleate
MAL	maleimide
Man	mannose
MCC	microcrystalline cellulose
ME	microemulsion
Miglyol® 812	medium-chain triglycerides
MLN	multiple lipid nanoparticles
MNP	magnetic nanoparticles
MonosteolTM	palmitate/stearate of propylene glycol
mPEG	methoxyl poly(ethylene glycol)
MPEG 2000	mono methoxy PEG 2000
MPS	mononuclear phagocyte system
mRNA	messenger RNA
MVC	maraviroc
MYS-25	polyethylene glycol 25 stearate
N.D.	no data
NE	nanoemulsion
NFT	neurofibrillary tangles
NK	natural killer
NLC	nanostructured lipid carriers
NNRTI	non-nucleoside reverse transcriptase inhibitors
NP	nanoparticles
NRTI	nucleoside reverse transcriptase inhibitors
NVP	nevirapine
OA	oleic acid
Oleic Plurol®	polyglyceryl 6 dioleate
OPG	O-palmitoylgalactose
OPM	O-palmitoylmannose
o/w	oil-in-water
PA	phenylalanine
PAA	poly(acrylic acid)
PBS	phosphate-buffered saline
PC	phosphatidylcholine
PE	phosphatidylethanolamine
PE-PEG2000	dipalmitoylphosphatidylethanolamine-N-[poly(ethylene glycol)2000]
PEG	polyethylene glycol
PEG-8-L	octaoxyehtylene laurate ester
Pept-DRV-SLN	peptide grafted-darunavir loaded SLN
PGDS	polyglyceryl-6-distearate
P-gp	P-glycoprotein
PI	protease inhibitors
PLL	poly(L-lysine hydrochloride
Plurol® Oleique CC 497	polyglyceryl-3 dioleate
POPC	1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
POPG	1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)
PPIX	protoporphyrin IX
Precirol® ATO 15	glyceryl palmitostearate
PrEP	pre-exposure prophylaxis
ProddINP	glycerolipidic prodrug of ddI
PS	phosphatidylserine
PVA	poly vinyl alcohol
RAL	raltegravir
RES	reticuloendothelial system
RISC complex	RNA-induced silencing complex
RNAi	RNA interference
RPV	rilpivirine
RT	reverse transcriptase
RTV	ritonavir
SA	stearylamine
SARS-CoV-2	severe acute respiratory syndrome coronavirus 2
SDS	sodium dodecyl sulfate
SEDDS	self-emulsifying drug delivery systems
SFV	sifuvirtide
SGR	somatic gene recombination
siRNA	small interference ribonucleic acid
SL	soy lecithin
SLN	solid lipid nanoparticles
SM	sphingomyelin
SMEDDS	self-micro emulsifying delivery systems
Smix	surfactant and cosurfactant mix
SNEDDS	self-nanoemulsifying drug delivery systems
Softisan® 100	hydrogenated coco-glycerides
Solutol® HS15	polyoxyl 15 hydroxystearate
SPC	soy phosphatidylcholine
SQV	saquinavir
SQVM	saquinavir mesylate
S-SNEOF	solid self-nanoemulsifying oily formulations
TAM	thymidine analog mutations
T-20	enfuvirtide
TDF	tenofovir disoproxil fumarate
TFV	tenofovir
TPV	tipranavir
Transcutol® HP	diethyleneglycol monoethyl ether
Transcutol® P	diethylene glycol monoethyl ether
UNAIDS	Joint United Nations Program on HIV infection/AIDS
U.S. FDA	United States Food and Drug Administration
VE	α-tocopherol
w/o	water-in-oil
w/w	weight/weight
wt	weight