Figure 3.

(a) Number of trials required for transgenic mice (TGM) and age-matched normal controls to learn an eight-choice maze across lifespan. Regression lines had the following equations: untreated TGM (y = 13.37(x²) − 126.54(x) + 313.96); untreated normal mice (y = 3.72(x²) − 36.92 (x) + 118.76) and treated (antiaging supplement) TGM (y = −9.19(x) + 65.49). Age in days is indicated above the X-axis. (b) Total errors committed during learning an eight-choice maze by TGM and normal controls across lifespan. Regression lines had the following equations: untreated TGM (y = 77.19 (x²) − 755.66(x) + 1888.15); untreated normal mice (y = 6.7(x²) − 47.15(x) + 206.74) and treated (antiaging supplement) TGM (y = −70.01x + 459.76). Age in days is indicated above the X axis. Data from Lemon et al. [97].