Table 1.
Changes in oxidative stress biomarkers during an example ISS mission [59].
| Compound Analyzed. | Example Pre-Flight Value | Example Post-Flight Value | Normal Ranges Observed in-Flight |
Maximal Changes Observed Post-Flight (Percentage Change from Pre-Flight) |
|---|---|---|---|---|
| Total Antioxidant Capacity | 1.54 | 1.47 | 1.29–1.83 | Decreased up to 30% |
| Superoxide Dismutase (SOD) | 1318 | 1172 | 1092–1817 | Decreased 10–30% |
| Glutathione Peroxidase | 51.5 | 50.8 | 27.5–73.6 | Decreased 5–15% |
| Malondialdehyde (MDA) | 0.8 | 0.6 | 0–2.00 | Increased 100–200% |
| 4-OH-alkenal | 0.45 | 0.45 | 0–2.00 | Increased 50–150% |
| Urinary 8OHdG | 3.2 | 3.7 | 0.49–7.29 | Increased 40–200% |