. 2021 Jul 23;19(8):408. doi: 10.3390/md19080408

Table 3.

Cytotoxic effects of compounds 1–3 against A549 and HT-29 cells.

Compounds	IC₅₀ (μM) ^a
Compounds	HT-29	A549
Epiremisporine F (1)	44.77 ± 2.70 ^c	77.05 ± 2.57 ^c
Epiremisporine G (2)	35.05 ± 3.76 ^d	52.30 ± 2.88 ^d
Epiremisporine H (3)	21.17 ± 4.89 ^e	31.43 ± 3.01 ^d
5-FU ^b	17.47 ± 1.67 ^e	10.57 ± 1.89 ^d

^a The IC₅₀ values were calculated from the slope of dose–response curves (SigmaPlot). Values are expressed as mean ± SEM (n = 3). ^c p < 0.05; ^d p < 0.01; ^e p < 0.001 compared with the control. ^b 5-Fluorouracil (5-FU) was used as a positive control.