Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 10;11(8):813. doi: 10.3390/life11080813

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The correlation between the mRNA expression levels of hub proteins with the drug response to immunotherapy (atezolizumab/anti-PD-L1) in the validation data set (Imvigor210). (A) The box plot revealed that high BUB1 expression was associated with the better response to immunotherapy (p < 0.05). (B) The box plot revealed that high CCNB2 expression was associated with the better response to immunotherapy (p < 0.05). (C) The box plot revealed that high CDC6 expression was associated with the better response to immunotherapy (p < 0.05). (D) The box plot revealed that high CDC20 expression was associated with the better response to immunotherapy (p < 0.05). (E) The box plot revealed that high CDK1 expression was associated with the better response to immunotherapy (p < 0.05). (F) The box plot revealed that high MCM2 expression was associated with the better response to immunotherapy (p < 0.05). Abbreviation: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.