Table 2.

Eleutherococcus senticosus studies.

Study Objectives	Study Design	Main Results	References
Examine the effects of Eleutherococcus senticosus extract on physical working capacity.	Six men, aged 21–22 years, participated in the study. They were in the control group, placebo group, and the group that received 2 mL ethanol extract (125 mg dried extract) Eleutherococcus senticosus twice daily. Period of study—8 days.	Increased maximal oxygen uptake, oxygen pulse, total work, and exhaustion time.	[46]
Examine the effects of Eleutherococcus senticosus during maximal and submaximal aerobic exercise.	Twenty men and women, aged 37 ± 8 years, participated in the study. There were 10 participants who received 3.4 mL Eleutherococcus senticosus extract; 10 participants were in the placebo group. Period of study—8 weeks.	No changes in heart rate, VO2, lactate.	[48]
Assessment of the effects of Eleutherococcus senticosus on metabolism, endurance capacity, and cardiovascular functions.	Nine men, aged 19 ± 2.1 years, participated in the study. The participants received 800 mg daily of Eleutherococcus senticosus or placebo. Period of study—8 weeks.	Decreased blood glucose levels. Increased VO2, endurance time, heart rate, and free fatty acids.	[49]
Assessment of the impact of Eleutherococcus senticosus on quality of life.	Twenty volunteers, aged over 65 years, participated in the study. There were 10 participants who received 300 mg/day Siberian ginseng extract and 10 participants who were in placebo group. Period of study—2 months.	Improved mental health and social functioning, but prolonged use decreased these improvements. Blood pressure was not affected.	[50]
Assessment of the influence of Eleutherococcus senticosus on physical fitness and cellular defence.	Forty-six men and women, aged 23–73 years, participated in the study. There were 31 participants who received 75 drops of Eleutherococcus senticosus extract daily and 15 participants who received 120 drops of Echinacea extract daily for one month.	Decreased total cholesterol, LDL, triglycerides, free fatty acids, and glucose. Increased maximal oxygen consumption (VO2max).	[51]
Examine the effects of a dietary supplement containing Eleutherococcus senticosus extract on burnout symptoms.	Eighty-seven volunteers, aged 27–63 years, participated in the study. There were 44 participants who had an intake of 100 mg dry extract from Eleutherococcus senticosus; 43 were in the placebo group. Period of study—12 weeks.	Decreased fatigue score and Beck depression.	[52]
Evaluate the effects of Eleutherococcus senticosus extract on stress.	One-hundred and thirty women and men, aged 30–50 years, participated in the study. There were 49 participants who received 120 mg/day of dry Eleutherococcus senticosus extract, 40 participants who worked out, and 41 who worked out and took 120 mg/day dry extract. Period of study—2 months.	Improvement in fatigue, exhaustion, sleep, and restlessness.	[52]
Examine physiological reactions from the intake of Eleutherococcus senticosus on cyclists.	Nine men, aged 28 ± 2 years, participated in the study. The participants received 1200 mg per day of Eleutherococcus senticosus extract for 7 days and the placebo for 7 days.	No difference in respiratory exchange ratio, oxygen consumption, heart rate, perceived exertion, plasma lactate, plasma glucose.	[53]
Evaluate the effects of Eleutherococcus senticosus during the training process in fitness.	In the second series of study, 17 men and women participated; 10 of them received Eleutherococcus senticosus extract, and 7 participants were in the controlled group.	Decreased body weight. Increased physical endurance and performance.	[54]