Table 2.

The effects of saffron supplementation on blood pressure.

	NO	WMD (95%CI)	p Value	P Heterogeneity	I2 (%)
Effect of saffron supplementation on SBP
Overall effect	10	−0.65 (−1.12, −0.18)	0.006	0.049	46.9%
Baseline SBP (mmHg)
<120	6	−1.57 (−2.73, −0.41)	0.008	0.565	0.0%
≥120	4	−0.47 (−0.98, 0.03)	0.068	0.017	70.6%
Duration
<12	5	−0.51 (−0.99, −0.03)	0.035	0.729	0.0%
≥12	5	−4.00 (−6.34, −1.67)	0.001	0.155	40.0%
Intervention dose (mg)
≥100	7	−0.56 (−1.03, −0.09)	0.019	0.160	35.1%
<100	3	−4.50 (−7.61, −1.40)	0.004	0.436	0.0%
Intervention type
Saffron	7	−0.58 (−1.05, −0.11)	0.016	0.136	38.4%
Crocin	3	−5.84 (−9.81, −1.87)	0.004	0.755	0.0%
Effect of saffron supplementation on DBP
Overall effect	8	−1.23 (−1.64, −0.81)	<0.001	0.928	0.0%
Baseline DBP (mmHg)
<80	5	0.66 (−2.50, 3.83)	0.681	0.959	0.0%
≥80	3	−1.26 (−1.68, −0.84)	<0.001	0.800	0.0%
Duration
<12	5	−1.25 (−1.68, −0.83)	<0.001	0.883	0.0%
≥12	3	0.45(−2.77, 3.69)	0.782	0.882	0.0%
Intervention dose (mg)
≥100	7	−1.23 (−1.65, −0.81)	<0.001	0.871	0.0%
<100	1	−1.01 (−7.94, 5.92)	0.775	-	-
Intervention type
Saffron	6	−1.23 (−1.65, −0.81)	<0.001	0.806	0.0%
Crocin	2	−0.38 (−5.89, 5.13)	0.892	0.769	0.0%

Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure.