Table 12.
Patents pertaining to Harpagophytum and its preparations.
| Title | Date | Number |
|---|---|---|
| Food supplement | 4/3/1984 | US19810287235 |
| Therapeutically active mixture | 11/8/1984 | DE19833316726 |
| Homeopathic remedy for the treatment of rheumatic disorders | 11/19/1987 | DE19863616054 |
| Plant-based medicinal composition for internal use | 4/22/1988 | FR19860014608 |
| Medicinal combination based on plants and trace elements for the treatment of rheumatism and inflammatory states | 11/10/1988 | FR19870006450 |
| Process for the preparation, by extracting, of Harpagophytum | 7/13/1992 | KR19890016112 |
| Anti-pruritic cosmetic composition containing Harpagophytum root extract | 1/27/1993 | EP19920402100 |
| Preparation of concentrated plant extract, particularly from Harpagophytum procumbens | 8/7/1997 | DE1996103788 |
| Harpagosid-angereicherter Extrakt aus Harpagophytum procumbens und Verfahren zu seiner Herstellung [harpagoside- enriched extract of H. procumbens and its manufacture] | 10/2/1997 | DE1996151290 |
| A purified extract from Harpagophytum procumbens and/or Harpagophytum zeyheri, a process for its preparation and its use | 12/18/1997 | |
| Skin care composition contains peroxidized fatty substance, e.g., unsaturated vegetable oils and plant extract | 3/20/1998 | FR19960011438 |
| Natural composition for treating bone or joint inflammation | 11/26/1998 | WO1998US10758 |
| Micro-nutritional compositions having a therapeutic effect containing polyunsaturated fatty acids, trace elements, and vitamins | 7/16/1999 | FR19980000331 |
| A method of producing high anti-inflammatory activity extracts from Harpagophytum procumbens | 10/6/1999 | GB19980006971 |
| Effervescent preparation containing a plant extract | 6/16/1999 | EP0922450A1 |
| Method for producing high activity extracts from Harpagophytum procumbens | 3/6/2001 | US19990280499 |
| Harpagoside-enriched extract from Harpagophytum procumbens and processes for producing the same | 8/28/2001 | US19990155043 |
| Dietary supplement | 12/18/2001 | JP20000172296 |
| Pharmaceutical preparation containing Cibotii rhizoma and Harpagophytum procumbens DC extracts as main ingredients | 6/3/2002 | KR20000071397 |
| Skin care preparation | 6/4/2002 | JP20000402968 |
| Pharmaceutical composition with anti-atherosclerotic activity | 6/5/2002 | EP20010128629 |
| Use of harpagide-related compound as prophylactic and therapeutic agent of osteoporosis, arthritis, and disc and pharmaceutical composition containing compound as effective ingredient | 11/16/2002 | KR20000071497 |
| Composition useful for treating or preventing osteoarthritis, especially in horses, containing extract(s) of Equisetum arvense, Symphytum officinale, and/or Harpagophytum procumbens | 3/27/2003 | DE2001143146 |
| Use of active substance mixtures containing tocopherols and Harpagophytum procumbens extracts for the preparation of a drug against rheumatic arthritis | 12/17/2003 | EP20020012765 |
| Chewing gum composition with vegetal additives | 7/29/2004 | WO2003EP14600 |
| Pain-relieving agent containing extract of Harpagophytum procumbens, Corydalis turtschanovii, and Atractylodes japonica | 2/5/2005 | KR20030052489 |
| Treating or preventing renal diseases, dysfunction, and/or damage, e.g., degenerative and/or inflammatory renal disease, using Harpagophytum extract or harpagoside | 3/10/2005 | DE2003126556 |
| Phyto-composition for the treatment of articular diseases | WO2005092355 | |
| Use of devil’s claw (Harpagophytum procumbens) root extracts for endometriosis treatment | 11/2/2006 | WO2006EP61831 |
| A method for separating harpagide from Harpagophytum procumbens | 2/5/2007 | KR20050102609 |
| Activator of peroxisome proliferator-activated receptor (PPAR) | 5/17/2007 | JP20050317156 |
| Adjuvant composition for physiotherapy | 7/24/2007 | KR20060005183 |
| Maillard reaction inhibitor, skin care preparation containing the same, and food and beverage | 10/4/2007 | JP20060080104 |
| Phyto-composition for the treatment of joint diseases | 12/13/2007 | US20050594439 |
| Natural remedy–dietary supplement combination product | 9/4/2008 | US20060815432 |
| Root extract of Harpagophytum for stimulating hair growth | 5/27/2009 | EP20070802633 |
| Skin care preparation, oral composition, and food and drink | 10/22/2009 | JP20080091677 |
| Novel method for preparing purified extracts of Harpagophytum procumbens | 12/9/2010 | US20080599146 |
| Animal food compositions | 7/21/2011 | WO2010US60804 |
| Compositions comprising plant extracts and use thereof for treating inflammation | 10/27/2011 | US200913120739 |
| Anti-inflammatory composition | 12/21/2011 | EP20110170436 |
| Antirheumatic body cream composition | 12/30/2011 | RO20110000644 |
| Pharmaceutical composition for preventing and treating metabolic bone disease comprising of Harpagophytum | 6/18/2012 | KR20110147135 |
| Phyto-concentrated composition, useful as antispasmodic relaxant, and muscular comfort to, e.g., enhance relaxation of painfully contracted muscle tissue, comprises, e.g., cannabis sativa and an excipient comprising, e.g., castor oil | 10/12/2012 | FR20110001030 |
| Nonabrasive toothpaste containing enzyme papain, Harpagophytum extract d,l-pyrrolidone carboxylate n-cocoyl ethyl arginate, and sodium fluoride | 7/20/2013 | RU20120101119 |
| Cosmetic composition for calming and applying an electric current of skins and manufacturing the same | 12/27/2013 | KR20120065152 |
| Anti-rheumatism medicinal liquor and preparation method thereof | 3/19/2014 | CN20131645408 |
| Composition containing chondroitin sulfate and hyaluronidase | 12/10/2014 | RU20130123301 |
| Mucoadhesive devil’s claw extracts (Harpagophytum procumbens) and uses thereof | 3/11/2015 | EP20140184267 |
| Compositions for alleviating, preventing, or treating pain comprising Harpagophytum procumbens and Acanthopanax senticosus extracts as active ingredients | 6/8/2015 | KR20130146128 |
| Traditional Chinese medicine composite for treating gout | 7/8/2015 | CN20151209743 |
| Cell line cultures from plants belonging to the Harpagophytum genus | 1/4/2018 | WO2017EP65814 |
| Method for preparing purified extracts of Harpagophytum procumbens | 30/10/2018 | US20100311675A1 |
| Oral herbal pain killer formulations | 15/10/2020 | WO2020208395A1 |
| Polyherbal transdermal patch for pain management and its process of preparation | 22/10/2020 | WO2020212820A2 |
| External medicine for inhibiting postoperative venous thrombosis and application thereof | 19/2/2021 | CN109589331B |
| Freedom (nutritional supplement) | 9/2/2021 | US20200060320A1 |