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. 1999 Mar;19(3):1950–1960. doi: 10.1128/mcb.19.3.1950

FIG. 7.

FIG. 7

NADPH oxidase inhibitors blocked NF-κB activation by IL-1β in monocytic cells. Nuclear extracts were prepared from Raji (A), U937 (B), THP-1 (C), HCT116 (D), or MCF7 A/Z (E) cells, either untreated or stimulated with IL-1β (50 U/ml). The same cells were preincubated for 1 h prior to IL-1β stimulation with increasing concentrations of DPI or PAO, as indicated in the figure. These extracts were analyzed by EMSA for binding to a specific κB probe.

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