Table 1.

Spray drying conditions for organic solution advanced spray drying in closed-mode under ultra-high purity nitrogen gas for (Ang (1—7), PNA5, Trehalose) spray-dried systems, and (co-SD Ang (1—7):Trehalose, PNA5:Trehalose) co-spray-dried systems.

Formulations (Powder Composition = Molar Ratio)	SD Ang (1—7) SD PNA5 co-SD Ang (1—7):Trehalose (25:75) co-SD PNA5:Trehalose (25:75)	co-SD PNA5:Trehalose (20:80)
Feed concentration in solvent (% w/v)	0.125	2.5
Solvent	Methanol	Methanol
Aspiration gas: ultra-high purity nitrogen gas (L/hour)	670 (55 mm in height)	670 (55 mm in height)
Inlet temperature (°C)	150	150
Outlet temperature (°C)	47–53	60
Inert loop temperature (°C)	−15	−15
Pump rate (%)	Low (25%) (7.5 mL/min)	Low (25%) (7.5 mL/min) and Medium (50%) (15 mL/min)
Aspirator (%)	100 (35 m3/h)	100 (35 m3/h)