Table 2.

Concurrent particle beam therapy combined with chemotherapy for pancreatic cancer.

Author	N	RT	Dose	Chemotherapy	Treatment	Outcome
Hong [46]	25	proton	30GyRBE/10fr 25GyRBE/5fr	capecitabine	preoperative	OS: 75%/1Y
Terashima [48]	50	proton	50GyRBE/25fr 70.2GyRBE/26fr 67.5GyRBE/25fr	gemcitabine	curative	OS: 76.8%/1Y, PFS: 64.3%/1Y
Hong [47]	50	proton	25GyRBE/5fr	capecitabine	preoperative	OS: 42%/2Y
Maemura [52]	10	proton	50GyRBE/25fr 67.5GyRBE/25fr	gemcitabine, S-1	curative	OS: 80, 45, 22.5%/1, 2, 3Y
Kim [49]	37	proton	45GyRBE/10fr	capecitabine, 5-FU	curative	OS: 75.7%/1Y, PFS: 64.8%/1Y, 19.3M
Jethea [50]	13	proton	50GyRBE/25fr	capecitabine, 5-FU	curative	OS: 62, 40%/1, 2Y, 16M
Hiroshima [51]	42	proton	50–67.5GyRBE/25-33fr	gemcitabine, S-1	curative	OS: 77.5, 50.8%/1, 2Y, 25.6M
Kawashiro [53]	72	carbon	52.8GyRBE/12fr 55.2GyRBE/12fr	gemcitabine, S-1 (n = 56)	curative	OS: 73, 46%/1, 2Y, 21.5M
Vitolo [58]		carbon	38.4GyRBE/4fr	FOLFIRINOX, gemcitabine	preoperative

Value in outcome represents overall survival rate, progression-free survival rate, and median survival time. OS: overall survival, PFS: progression-free survival.