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. 2021 Aug 19;11(8):808. doi: 10.3390/jpm11080808
ABC ATP binding cassette
ADC antibody-drug conjugate
ADCC antibody dependent cell cytotoxicity
AI aromatase inhibitor
AIB1 amplified in breast cancer 1
ALND axillary lymph node dissection
AR androgen receptor
ATM ataxia-telangiesctasia mutated
BC breast cancer
BCRP breast cancer resistant protein
BRCA breast cancer gene
BsAb bispecific antibody
CBR clinical benefice rate
CDK4/6 cyclin-dependent kinase
CR clinical response
CSC cancer stem cell
CTLA4 cytotoxic T lymphocyte-associated protein 4
DDFS distant disease-free survival
DFS disease-free survival
DLT dose-limiting toxicities
DoCB duration of clinical benefit
DoR duration of response
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ER estrogen receptor
FDA food and drug administration
gBRCAm germline BRCA mutation
HB-EGF heparin-binding EGF-like growth factor
HER2 human epidermal growth factor receptor 2
HGF hepatocyte growth factor
HIF1-α hypoxia-inducible factor 1 alpha
HR hormone receptor
HR hazard ratio
IAES incidence of adverse events
IDFS invasive disease-free survival
iEFS invasive events-free survival
IGF-1 insulin growth factor 1
IGF-1R insulin growth factor receptor 1
MAP microtubule associated protein
MAPK mitogen activated protein kinase
MBC metastatic breast cancer
MTD maximum tolerated dose
mTOR mammalian target of rapamycin
NAC neoadjuvant chemotherapy
ORR overall response rate
OS overall survival
PARP poly-(ADP-ribose) polymerase protein
PARPi poly-(ADP-ribose) polymerase protein inhibitor
pCR predicted complete response
PD-1 programmed cell death protein receptor
PDL-1 programmed cell death protein ligand
PFS progression-free survival
PI3K phosphoinositide 3-kinase
PPV personalized peptide vaccine
PR progesterone receptor
PR partial response
PTEN phosphatase and tensin homolog
Ras-ERK extracellular-signal-regulated kinase
RFS recurrence-free survival
SD stable disease
SERD selective estrogen receptor degrader
SERM selective estrogen receptor modulator
SLNB sentinel lymph mode biopsy
STnKLH sialyl-TN keyhole limpet hemocyanin
T-DM1 trastuzumab-emtansine
TKI tyrosine kinase inhibitor
TNBC triple-negative breast cancer
Trop2 trophoblast antigen 2
TTF time to treatment failure
TTP time to treatment progression
TTR time to treatment response
VEGF vascular endothelial growth factor