TABLE 2.
Relative mutation rates in short and long homonucleotide runs and the CAN1 gene in various pol2-4 mutants
| Strain genotype comparison | Relative mutation rate
|
||||
|---|---|---|---|---|---|
| A4 (−1) | A14 (−1) | A5 (+1) | A12 (+1) | Canr | |
| pol2-4 vs wild type | 6 | 2.2 | 7 | 1 | 2.3 |
| exo1 pol2-4 vs exo1 | 111 | 10 | 385 | 55 | 5.7 |
| msh2 pol2-4 vs msh2 | 37 | 2.5 | 309 | 1.6a | 17 |
| msh3 pol2-4 vs msh3 | NDb | 2.6 | ND | 1.1a | 2.2 |
| msh6 pol2-4 vs msh6 | ND | 1.7 | ND | 1.9 | 52 |
| msh3 msh6 pol2-4 vs msh3 msh6 | ND | 1 | ND | 1 | 49 |
a
No significant difference; the 95% confidence intervals for the mutation rate in these two strains overlap.
b
ND, not determined.