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Inhibition of the hepatitis C virus (HCV) replicon in cell assays. Evaluation of the potency and cytotoxicity of the protein in cell (Huh-5-2) assays. HCV replicon replication rate (luminescence, black bars) and cell survival (closed squares) were independently measured in cell culture by increasing protein concentration to determine EC50. * All luminescence and viability values were normalized considering the untreated control values (UTC).
