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General mechanisms of IgE mediated response to food allergens. Interaction between food allergens and IgE and its high-affinity FC receptor (FCER1) on basophils in circulation or mast cells present in mucosal tissues leading to their activation and consequent physiological response. Adapted from Renz, Allen, Sicherer, Sampson, Lack, Beyer and Oettgen [22]. Adapted with permission from Ref. [22]. Copytright 2018. Springer Nature.
