Table 2.

Proteins With Differential Expression Between KC and Control Group Using SWATH-MS

Protein	Uniprot Code	Protein Abbreviation	P Value	FC
Plastin 3	sp|P13797|PLST_HUMAN	PLS3, PLST	<0.0001	1.736
DNA dC→dU-editing enzyme APOBEC-3A	sp|P31941|ABC3A_HUMAN	ABC3A, APOBEC3A	0.011	1.555
Tubulin α1C chain	sp|Q9BQE3|TBA1C_HUMAN	TBA1C, TUBA1C	0.020	1.435
6-Phosphogluconate dehydrogenase, decarboxylating	sp|P52209|6PGD_HUMAN	6PGD, PGD	0.033	1.430
Cofilin 1	sp|P23528|COF1_HUMAN	CFL1, COF1	0.017	1.180
Annexin A2	sp|P07355|ANXA2_HUMAN	ANXA 2	0.044	1.155
Annexin A1	sp|P04083|ANXA1_HUMAN	ANXA 1	0.039	1.139
ρ GDP-dissociation inhibitor 1	sp|P52565|GDIR1_HUMAN	ARHGDIA	0.042	0.799
Heat shock cognate 71-kDa protein	sp|P11142|HSP7C_HUMAN	HSP7C, HPSA8	0.004	0.797
Latexin	sp|Q9BS40|LXN_HUMAN	LXN	0.029	0.655
Angiotensinogen	sp|P01019|ANGT_HUMAN	ANGT, AGT	0.028	0.604
Hemopexin	sp|P02790|HEMO_HUMAN	HEMO, HPX	0.014	0.547
α2-HS-glycoprotein	sp|P02765|FETUA_HUMAN	AHSG, FETUA	0.019	0.540
Transthyretin	sp|P02766|TTHY_HUMAN	TTHY, TTR	0.040	0.496
α1-Acid glycoprotein 1	sp|P02763|A1AG1_HUMAN	A1AG1, ORM1	0.018	0.483
Vitamin D binding protein	sp|P02774|VTDB_HUMAN	VTDB, GC	0.038	0.414
Serum albumin	sp|P02768|ALBU_HUMAN	ALB, ALBU	0.003	0.255
Serotransferrin	sp|P02787|TRFE_HUMAN	TRFE, TF	0.014	0.228

FC shown in upregulated proteins if FC > 1 or in downregulated proteins if FC < 1. Sample size:

KC = 25 participants, 25 eyes; controls = 25 participants, 25 eyes.