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. 2021 Aug 17;13(8):1280. doi: 10.3390/pharmaceutics13081280
ADME (Drug) Absorption, Distribution, Metabolism, and Excretion
ECVAM European Centre for the Validation of Alternative Methods
FDA U.S. Food and Drug Administration
HTS High-Throughput Screening
IECs Intestinal Epithelial Cells
JRC Joint Research Centre
MOC Multi-Organ Chip
MPS MicroPhysiological System
NAMs New Approach Methods
NAT Non-Animal Methods
OOC Organ-On-a-Chip
PAMPA Parallel Artificial Membrane Permeability Assay
PBKD Physiologically Based Kinetic and Dynamic
QSAR Quantitative Structure-Activity Relationship
VCBA Virtual Cell Based Assay