Table 1.

Clinical and Pathological Characteristics of COVID-19 and Control Samples.

Case No.	Age	Sex	Race	Smoking Status	Length of Hospital Stay	Immunosuppression	Ventilatory Support	Duration of MV	P/F Ratio	Lung Autopsy Findings
C1	36	M	Black	Yes	13	Tocilizumab, hydrocortisone	HFNC, MV	9 d	64	Acute bronchopneumonia and few microthrombi
C2	84	F	Black	Former	4	None	NC	none	191	Lungs with acute and chronic aspiration pneumonia, focal bronchopneumonia
C3	84	M	Black	N/A	1	None	HFNC	none	65	Reactive pneumocytes and fibrin thrombi with bilateral bronchopneumonia
C4	77	F	Black	N/A	15	Tocilizumab	HFNC	none	NA	Hyaline membrane formation and focal superimposed bronchopneumonia
C5	51	F	Black	Yes	12	Hydrocortisone	HFNC, MV	7 d	64	Diffuse alveolar damage and mucous plugging
C6	82	F	Black	Former	13	Hydrocortisone	HFNC, MV	13 d	63	Diffuse alveolar damage, hemorrhage, aspiration pneumonia
C7	84	F	Black	No	5	Hydrocortisone	NC	none	N/A	Acute and chronic aspiration pneumonia
C8	40	M	Black	No	25	Tocilizumab	MV	22 d	62	Diffuse alveolar damage, thromboemboli, areas of infarction
C9	80	F	Black	Former	1	None	NC	none	N/A	Diffuse acute pneumonia and focal platelet thrombi
C10	78	F	Black	Former	5	None	MV	6 d	141	Diffuse alveolar damage and intraalveolar hemorrhage
R1	58	M	N/A	Yes	N/A	N/A	MV	N/A	N/A	Recent hemorrhage (trauma)
R2	59	F	N/A	Yes	N/A	N/A	MV	N/A	N/A	Patchy nonspecific interstitial fibrosis
R3	53	M	N/A	Former	N/A	N/A	MV	N/A	N/A	Emphysema
R4	35	M	N/A	Yes	N/A	N/A	MV	N/A	N/A	Emphysema, patchy nonspecific interstitial fibrosis
R5	59	F	N/A	Yes	N/A	N/A	MV	N/A	N/A	Patchy nonspecific interstitial fibrosis

Definition of abbreviations: C = COVID-19 case number; COVID-19 = coronavirus disease; HFNC = high-flow NC; MV = mechanical ventilation; N/A = not applicable; NC = nasal cannula; R = Gift of Hope case number.