Table 2.
GO Term Enrichment for Genes Differentially Expressed on Day 7 in COPD HBEC Compared with Normal HBEC after Repopulation on Normal Bronchial Scaffolds
| GO Biological Process | Fold Enrichment | FDR |
|---|---|---|
| Cilium organization (GO:0044782) | 2.6 | 5.7 × 10−15 |
| Cilium assembly (GO:0060271) | 2.6 | 7.2 × 10−14 |
| Plasma membrane–bounded cell projection assembly (GO:0120031) | 2.3 | 2.1 × 10−12 |
| Cell projection assembly (GO:0030031) | 2.3 | 3.0 × 10−12 |
| Cell projection organization (GO:0030030) | 1.7 | 3.2 × 10−11 |
| Plasma membrane–bounded cell projection organization (GO:0120036) | 1.7 | 1.6 × 10−10 |
| Microtubule bundle formation (GO:0001578) | 3.9 | 3.7 × 10−9 |
| Microtubule-based process (GO:0007017) | 1.8 | 1.0 × 10−8 |
| Axoneme assembly (GO:0035082) | 4.5 | 2.9 × 10−8 |
| Cilium movement (GO:0003341) | 4.5 | 5.7 × 10−8 |
Shown are the GO biological process terms for which there is an overrepresentation among the differentially expressed genes relative to the reference list, which consisted of all GO-annotated genes that were detected in at least one RNA-Seq sample. Shown are the 10 terms with the lowest FDR for each analysis.