Table 2.
Clinical and radiological presentations of pulmonary cryptococcosis.
| Clinical Symptoms | N = 321, n (%) |
|---|---|
| No | 111 (34.6) |
| Yes | 210 (65.4) |
| Cough | 129 (40.2) |
| Fever | 42 (13.1) |
| Shortness of breath | 23 (7.2) |
| Chest pain | 21 (6.5) |
| Hemoptysis | 10 (3.1) |
| Dizziness/headache | 10 (3.1) |
| Decreased appetite/weight loss | 8 (2.5) |
| Fatigue | 7 (2.2) |
| Chillness | 6 (1.9) |
| Altered consciousness/neurological deficit | 4 (1.2) |
| Extent of disease | N = 321, n (%) |
| Extrapulmonary involvement | |
| No | 299 (93.1) |
| Yes | 22 (6.9) |
| Central nervous system (CNS) | 18 (5.6) |
| Fungemia | 8 (2.5) |
| Others * | 4 (1.2) |
| Findings on chest computed tomography | N = 305, n (%) |
| Extent of pulmonary cryptococcosis | |
| Single lobe | 185 (60.7) |
| Multiple lobes # | 120 (39.3) # |
| Radiological presentations | |
| Multiple nodules/masses with or without cavitation,$ | 161 (52.8) |
| Consolidation | 52 (17.0) |
| Solitary nodule/mass with or without cavitation $ | 48 (15.7) |
| Ground glass opacity | 3 (1.0) |
| Mixed pattern $,& | 41 (13.4) |
| Associated findings | |
| Pleural effusion | 11 (3.6) |
| Lymphadenopathy | 5 (1.6) |
* Includes 1 with urinary tract infection, 1 with paraspinal abscess, and 2 with neck lymph node infection. # Includes 88 patients with involvement of both lungs. $ Among patients with nodule(s) or mass(es), a total of 37 patients with cavitation. & Most common are consolidation mixed with nodule(s)/mass(es) (n = 29).