Table 5.
Univariate analysis of radiological presentations and the extent of disease.
| Factors | N # | Cavitation | p Value * | Single Nodule or Mass | p Value * | Multilobar Involvement | p Valve * | N $ | Extrapulmonary Involvement | p Value * | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | <65 years | 198 | 25 (12.6) | 0.855 | 42 (21.2) | <0.001 | 54 (27.3) | <0.001 | 208 | 12 95.8) | 0.356 |
| ≥65 years | 107 | 12 (11.2) | 6 (5.6) | 66 (61.7) | 113 | 10 (8.8) | |||||
| Gender | Female | 129 | 15 (11.6) | 0.861 | 25 (19.4) | 0.153 | 45 (34.9) | 0.193 | 138 | 9 (6.5) | 1.000 |
| Male | 176 | 22 (12.5) | 23 (13.1) | 75 (42.1) | 183 | 13 (7.1) | |||||
| Smoking status | Non-smokers | 223 | 25 (11.2) | 0.664 | 37 (16.6) | 0.702 | 86 (38.6) | 0.475 | 234 | 16 (6.8) | 0.793 |
| Smokers | 66 | 9 (13.6) | 9 (13.6) | 29 (43.9) | 68 | 5 (7.4) | |||||
| Comorbidities | No | 113 | 10 (8.8) | 0.383 | 22 (19.5) | 0.177 | 29 (25.7) | <0.001 | 117 | 2 (1.7) | 0.004 |
| Single | 126 | 18 (14.3) | 20 (15.9) | 55 (43.7) | 137 | 11 (8.0) | |||||
| Multiple | 66 | 9 (13.6) | 6 (9.1) | 36 (54.5) | 67 | 9 (13.4) | |||||
| Symptoms | No | 110 | 6 (5.5) | 0.006 | 27 (24.5) | 0.003 | 32 (29.1) | 0.007 | 111 | 2 (1.8) | 0.009 |
| Yes | 195 | 31 (15.6) | 21 (10.8) | 88 (45.1) | 210 | 20 (9.5) | |||||
| Blood CrAg test | <1:128 | 203 | 21 (10.3) | 0.115 | 35 (17.2) | 0.001 | 69 (34.0) | <0.001 | 215 | 5 (2.3) | < 0.001 |
| ≥1:128 | 84 | 15 (17.9) | 3 (3.6) | 50 (59.5) | 88 | 17 (19.3) | |||||
CrAg, cryptococcal antigen. * By Fisher’s exact test. # Analysis of radiological presentations. $ Analysis of extrapulmonary involvement.