Table 1.

A classification of proteins that show significantly different levels when comparing AML cells with strong and weak antiproliferative effects of chloroquine. The gene names are shown to the right. The proteins are described in detail in Table S3 and the results of the proteomic analyses are summarized in Table S4.

Classification	Proteins (Referred to by Their Corresponding Gene Names)
Autophagy regulation	SIGIRR, PGPEP1, STK38L, DAP3, YBX1, CSDE1, PRMT1, HGSNAT, FAF1, FAM105A
Mitophagy regulation	ATPIF1, PGPEP1, STK38L
Cytoskeletal protein	DNAJC1, SIGIRR, TUBA1A, NUDCD3, TUBB6, TPPP3
Intracellular trafficking	SYTL1, WDR81
Endoplasmic reticulum	WDR81, LEPRE1, DPM3, CALU, SERPINH1, LY75
Lysosomal protein	WDR81, LY75, HGSNAT
Mitochondria, metabolism	SARDH, SLC2A5, ATPIF1, H6PD, DAP3, MMS19, HK2
Extracellular release	PPBP, YBX1
Cell surface/adhesion	HLA-E, EPB41L2, ITGB3, ITGA2B, DPYSL3
Intracellular signaling	DNAJC1, SIGIRR, STK38L, FAF1, TSTD1
Transcription	SUGP2, SAP30L, PGPEP1, GTF2E2, NPM3, CRIP2