Figure 1.

Literature search strategy showing the combination of search terms used and the number of articles included in the manuscript and the total number of articles retrieved by each search for each outcome. Most publications were concerning GABA as a neurotransmitter, its metabolism, and its derivatives and prodrugs such as pregabalin, gabapentin, and articles describing GABA function as an innate metabolite in the human body. T, total articles retrieved; N, articles included in the review.