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. 2021 Aug 16;26(16):4949. doi: 10.3390/molecules26164949

Figure 6.

Figure 6

Drug penetration assay for validation of drug resistance in the ASM using the auto-fluorescent drug (DOX). (A) Images of DOX penetration in HepG2 ASM and CSM and quantitatively analyzed drug penetration ratios in each 3D model. The penetrated DOX fluorescence was calculated at 14.69% and 72.2%, respectively. (B) Images of DOX penetration in HepG2 ASM and CSM and quantitatively analyzed drug penetration ratios in each 3D model. The penetrated DOX fluorescence was calculated at 5.75% and 86.37%, respectively. * p < 0.05, ** p < 0.01.