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. 2021 Jul 27;13(8):1152. doi: 10.3390/pharmaceutics13081152

Figure 3.

Figure 3

Action of ion release from MBG-75S on cell size, cell complexity, intracellular reactive oxygen species, and cytosolic calcium of MC3T3-E1 pre-osteoblasts and endothelial progenitor cells (EPCs) after 24 h. During cell culture, 1 mg/mL of MBG-75S was deposited on transwell inserts (MBG T), allowing the ions to diffuse through the pores in order to evaluate only the action of the released ions on each cell type. Control cells were cultured in the presence of transwell inserts without material (CTRL T) in parallel. Statistical significance: *** p < 0.005.