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. 2021 Aug 17;26(16):4978. doi: 10.3390/molecules26164978

Figure 6.

Figure 6

Levels of TBARS in the livers collected from FeDex-loaded mice that had been treated with DI, NAC and PRBF. In the preventive study, mice were treated with DI, NAC (100 mg/kg) and PRBF (5 mg AE/kg) for 14 d. This was followed by a single ip injection with 10 mg FeDex after the last oral dose was administered on day 14. Mice were then sacrificed; their internal organs were dissected and liver TBARS concentrations were determined. In the therapeutic study, mice were ip injected with 10 mg FeDex together with DI, NAC (100 mg/kg) and PRBF (5 mg AE/kg) for 14 d. Mice were then sacrificed, their internal organs were dissected and TBARS concentrations in the livers were determined. Data are expressed as mean ± SD values (n = 6). a p < 0.05 when compared with DI alone in the preventive study and b p < 0.05 when compared with DI in FeDex-loaded mice; d p < 0.05 when compared with DI alone and e p < 0.05 when compared with DI in FeDex-loaded mice in the therapeutic study. Abbreviations: AE = anthocyanin equivalent, PRBF = plasma-treated Riceberry™ rice flour, DI = deionized water, FeDex = iron dextran, NAC = N-acetylcystein, SD = standard deviation, TBARS = thiobarbituric acid-reactive substances.