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. 2021 Jul 21;14(8):702. doi: 10.3390/ph14080702

Scheme 3.

Scheme 3

Solid-phase synthesis of acetyl tetrapeptide-15. HOBt: hydroxybenzotriazole; DIC: N,N′-diisopropylcarbodiimide; DMAP: 4-(dimethylamino)pyridine; DIPEA: N,N-diisopropylethylamine. Reproduced from reference with permission from the Centre National de la Recherche Scientifique (CNRS) and the Royal Society of Chemistry [46].