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. 2021 Aug 5;11(8):789. doi: 10.3390/life11080789

Figure 3.

Figure 3

PRMT1 repressed the transcriptional function of p53. (A–D) Reporter gene assays were performed in HCT116 p53−/− (A,C) and H1299 p53−/− cells (B,D) transfected with p53-Luc reporter plasmid, together with plasmids expressing p53 and PRMT1-WT/mutant expression plasmids (A,B), or reporter plasmid and PRMT1-WT/mutant plasmids (C,D). The expression of FLAG-tagged PRMT1, HA-tagged p53, or endogenous p53 is shown on the right. Data were presented as the means ± SD and analyzed using one-way ANOVA. #, p > 0.05; *, p < 0.05; **, p < 0.01.