Table 4.
Anthropometric, hemodynamic, and biohumoral characteristics, stratified according to the presence or absence of rapid decline of renal function (>5 mL/min/1.73 m2/year).
| Rapid Decline of eGFR | No rapid Decline of eGFR | p | |
|---|---|---|---|
| (n = 200) | (n = 507) | ||
| Sex, m/f | 87/113 | 280/227 | 0.004 |
| Age, years | 62.3 ± 9.4 | 60.4 ± 11.1 | 0.034 |
| BMI, kg/m2 | 29.4 ± 6.1 | 29.1 ± 5.6 | 0.603 |
| SBP, mmHg | 142.3 ± 15.4 | 138.6 ± 14.9 | 0.005 |
| DBP, mmHg | 82.6 ± 10.7 | 83.1 ± 10.1 | 0.637 |
| Pulse pressure, mmHg | 59.5 ± 14.6 | 55.6 ± 13.2 | 0.001 |
| Fasting glucose, mg/dL | 105.5 ± 24.9 | 99.3 ± 15.4 | <0.0001 |
| Fasting Insulin, mU/mL | 12.9 ± 6.1 | 11.5 ± 5.1 | 0.001 |
| HOMA | 3.4 ± 2.1 | 2.8 ± 1.4 | <0.0001 |
| Cholesterol, mg/dL | 199.9 ± 37.2 | 198.4 ± 48.4 | 0.694 |
| LDL, mg/dL | 121.7 ± 40.1 | 115.4 ± 33.6 | 0.063 |
| HDL, mg/dL | 48.4 ± 14.6 | 50.5 ± 15.2 | 0.103 |
| Hypercholesterolemic, mg/dL | 137.9 ± 87.1 | 135.6 ± 90.1 | 0.801 |
| Creatinine, mg/dL | 0.97 ± 0.1 | 1.01 ± 0.3 | <0.0001 |
| eGFR, mL/min/1.73 m2 | 93.8 ± 24.8 | 74.1 ± 24.4 | <0.0001 |
| Uric acid, mg/dL | 7.5 ± 2.2 | 4.7 ± 2.1 | <0.0001 |
| hs-CRP, mg/dL | 2.7 ± 2.1 | 2.9 ± 2.2 | 0.180 |
| Pre-bronchodilator FEV1, % | 79.8 ± 21.2 | 83.8 ± 22.5 | 0.032 |
| FEV1/FVC | 0.60 ± 0.08 | 0.62 ± 0.07 | 0.019 |
Abbreviations: eGFR, estimated glomerular filtration rate; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA, homeostatic model assessment; LDL, low-density lipoprotein; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; FEV1, forced expiratory volume in the 1st second; FVC, forced vital capacity.