Table 1.
Clinical characteristics by GNRI of (A) males and (B) females.
| (A) | |||
| Variables | GNRI | p Value | |
| ≥92 (n = 631) | <92 (n = 202) | ||
| Age, years | 63.4 ± 12.3 | 72.3 ± 11.1 | <0.001 |
| Dialysis vintage, months | 62 (26–124) | 67 (29–133) | 0.556 |
| Diabetes mellitus, n (%) | 251 (40.1) | 76 (37.8) | 0.564 |
| Smokers (ever, current), n (%) | 427 (67.8) | 143 (71.1) | 0.371 |
| Dry weight, kg | 61.7 ± 10.0 | 52.6 ± 9.4 | <0.001 |
| Hemoglobin level, g/dL | 11.0 ± 1.1 | 10.5 ± 1.2 | <0.001 |
| CRP level, mg/L | 0.9 (0.5–2.8) | 2.7 (0.8–7.8) | <0.001 |
| Total cholesterol level, mg/dL | 151.5 ± 30.0 | 144.0 ± 31.8 | <0.001 |
| Cr level, mg/dL | 11.6 ± 2.9 | 9.4 ± 2.6 | <0.001 |
| Ca level, mg/dL | 9.0 ± 0.7 | 8.7 ± 0.8 | <0.001 |
| Pi level, mg/dL | 5.2 ± 1.2 | 4.9 ± 1.4 | <0.001 |
| ALP level, U/L | 217 (171–274) | 242 (187–292) | 0.004 |
| Intact-PTH level, pg/mL | 122 (67–188) | 101 (47–153) | 0.002 |
| Use of statins, n (%) | 110 (17.4) | 26 (12.9) | 0.127 |
| Use of VDRAs, n (%) | 388 (61.5) | 113 (56.0) | 0.161 |
| Use of Pi-binders, n (%) | 560 (82.3) | 146 (72.3) | 0.002 |
| Use of ESAs, n (%) | 560 (88.8) | 191 (90.2) | 0.016 |
| (B) | |||
| Variables | GNRI | p Value | |
| ≥92 (n = 329) | <92 (n = 180) | ||
| Age, years | 64.2 ± 11.3 | 70.8 ± 12.5 | <0.001 |
| Dialysis vintage, months | 96 (33–175) | 71 (31–133) | 0.022 |
| Diabetes mellitus, n (%) | 112 (34.6) | 43 (24.6) | 0.021 |
| Smokers (ever, current), n (%) | 66 (20.1) | 33 (18.4) | 0.647 |
| Dry weight, kg | 51.8 ± 11.0 | 42.9 ± 8.2 | <0.001 |
| Hemoglobin level, g/dL | 10.7 ± 1.1 | 10.7 ± 1.3 | 0.763 |
| CRP level, mg/L | 0.7 (0.5–1.9) | 0.7 (0.5–2.9) | 0.261 |
| Total cholesterol level, mg/dL | 172.0 ± 31.1 | 167.0 ± 36.0 | 0.042 |
| Cr level, mg/dL | 10.2 ± 2.2 | 8.6 ± 2.0 | <0.001 |
| Ca level, mg/dL | 9.2 ± 0.7 | 8.9 ± 0.8 | <0.001 |
| Pi level, mg/dL | 5.4 ± 1.3 | 5.2 ± 1.4 | 0.045 |
| ALP level, U/L | 239 (183–313) | 273 (191–336) | 0.036 |
| Intact-PTH level, pg/mL | 124 (69–195) | 120 (55–180) | 0.106 |
| Use of statins, n (%) | 96 (29.2) | 30 (16.7) | 0.002 |
| Use of VDRAs, n (%) | 199 (60.7) | 116 (64.4) | 0.402 |
| Use of Pi-binders, n (%) | 285 (86.9) | 1313 (74.0) | <0.001 |
| Use of ESAs, n (%) | 301 (91.5) | 165 (91.7) | 0.945 |
Data are presented as mean ± standard deviation or median (interquartile range) for continuous variables. Differences between groups were analyzed using the Mann–Whitney U test or chi-squared test. Abbreviations: GNRI, geriatric nutritional risk index; CRP, C-reactive protein; Cr, creatinine; Ca, calcium: Pi, phosphate; ALP, alkaline phosphatase; intact-PTH, intact parathyroid hormone; VDRAs, vitamin D receptor activators; ESAs, erythropoiesis-stimulating agents.