Table 3.

Hazard ratios for bone fractures in (A) males and (B) females.

(A)
Univariate	HR (95% CI)	p Value
GNRI, <92	3.51 (1.91–6.42)	<0.001
Covariate	HR (95% CI)	p Value
Age, ≥67 years	1.99 (1.04–3.81)	0.038
Dialysis vintage, ≥73 months	0.77 (0.39–1.50)	0.439
Smokers (ever, current), presence	0.79 (0.43–1.48)	0.470
CRP level, ≥1.0 mg/L	0.93 (0.50–1.72)	0.815
Ca level, ≥9.1 mg/dL	0.82 (0.42–1.65)	0.584
Pi level, ≥5.2 mg/dL	1.36 (0.73–2.55)	0.337
ALP level, ≥230 U/L	1.54 (0.82–2.89)	0.179
Intact-PTH level, ≥118 pg/mL	0.72 (0.37–1.38)	0.323
Use of VDRAs, presence	1.32 (0.70–2.51)	0.390
Use of Pi-binders, presence	0.62 (0.31–1.25)	0.181
GNRI, <92	2.94 (1.54–5.59)	0.001
(B)
Univariate	HR (95% CI)	p Value
GNRI, <92	2.47 (1.52–4.03)	<0.001
Covariate	HR (95% CI)	p Value
Age, ≥67 years	1.76 (1.02–3.04)	0.042
Dialysis vintage, ≥73 months	0.93 (0.55–1.55)	0.775
Smokers (ever, current), presence	0.65 (0.32–1.36)	0.255
CRP level, ≥1.0 mg/L	1.03 (0.61–1.72)	0.917
Ca level, ≥9.1 mg/dL	0.97 (0.56–1.66)	0.908
Pi level, ≥5.2 mg/dL	1.36 (0.80–2.30)	0.254
ALP level, ≥230 U/L	0.98 (0.57–1.67)	0.943
Intact-PTH level, ≥118 pg/mL	0.88 (0.52–1.47)	0.616
Use of VDRAs, presence	1.12 (0.66–1.90)	0.666
Use of Pi-binders, presence	0.58 (0.32–1.05)	0.072
GNRI, <92	2.05 (1.20–3.51)	<0.001

The presented HRs are for bone fractures. Categories for age, dialysis vintage, levels of CRP, Ca, Pi, ALP, and intact-PTH, as well as GNRI were calculated in accordance with the median value of the group. Abbreviations: CRP, C-reactive protein; Ca, calcium: Pi, phosphate; ALP, alkaline phosphatase; intact-PTH, intact parathyroid hormone; VDRAs, vitamin D receptor activators; GNRI, geriatric nutritional risk index.