Figure 4.

Degree of biofilm development of H. pylori 8064 treated with the tested plant extracts (A4/2 or A5/1) and their combination with tested synthetic compounds (amoxicillin (AMX), 3-bromopyruvate (3-BP), or sertraline (SER)) during the Bioflux-generated flow conditions. Bacteria were treated with substances as follows: MIC of a plant extract, ¼ × MIC of a plant extract + ¼ × MIC of AMX, ¼ × MIC of a plant extract + ¼ × MIC of 3-BP, or ¼ × MIC of a plant extract + ½ × MIC of SER. The study controls were microcapillaries colonized by bacteria not exposed to any antimicrobial substances. The p-value represented by *** is equal to <0.0001.