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Molecular size chromatograms of representative lots of group A, C, Y, W and X polysaccharides (A) and bulk conjugates (B) manufactured for Phase 3 trials with NmCV-5. A TSK 6000 + 5000PWXL column series was used with a PBS (pH 7.4) buffer. Vo and Vt markers eluted at 46.2 min and 99.2 min, respectively. Data were obtained at NIBSC.
