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Immunogenicity of NmCV-5 in BALB/c mice (EIGHT per group). Post dose-2 and post dose-3 polysaccharide-specific IgG from a pentavalent R&D lot were administered either with (■) or without (♦) aluminum phosphate adjuvant. The geometric mean of serotype-specific IgG concentrations in units/mL, were determined by ELISA. Error bars represent 95% confidence intervals. The study was performed at NIBSC.
