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. 2021 Jul 28;13(8):2589. doi: 10.3390/nu13082589

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of sub-chronic (15 days) administration of a 10 mg/kg dose of either oleoylethanolamide (OEA) or palmitoleylethanolamide (POEA). on the plasma levels of insulin (A) and analyzed the Homeostatic Model Assessment for Insulin Resistance (HOMA IR) (B) in male Sprague–Dawley rats. Data are expressed as means ± standard error of the mean (SEM) (n = 8 animals/group) analyzed by two-way ANOVA (diet and treatment and Bonferroni post hoc test). (*) p < 0.05 and (**) p < 0.01 significant differences compared with standard diet (STD) vehicle (VEH) group; (#) p < 0.05, (##) p < 0.01, and (###) p < 0.001 significant differences compared with hypercaloric cafeteria diet (HFD) VEH group.